Mehr

Researchers at the Kantonsspital St.Gallen have identified a new risk factor for inflammatory heart disease. As the scientific magazine Science reports in its November 15, 2019 issue, harmless gut bacteria can instruct the immune system to attack the heart, exacerbating damage and inflammation. These new findings make it possible for the first time to use targeted therapeutic approaches in this potentially fatal disease. Mehr

Ludewig and colleagues use a real-time CXCL13 reporter to resolve the molecular identity of the B cell-interacting reticular cell (BRC) landscape. Poised, BRC-defined microenvironments establish a feed-forward system that support the dynamic movement of B cells to engage antigen and helper T cells, securing efficient germinal center responses.

Mehr